circCUL2 regulates gastric cancer malignant transformation and cisplatin resistance by modulating autophagy activation via miR-142-3p/ROCK2

Abstract

Circular RNAs (circRNAs) are a class of noncoding RNAs (ncRNAs) and can modulate gene expression by binding to miRNAs; further, circRNAs have been shown to participate in several pathological processes. However, the expression and biological function of circCUL2 in gastric cancer (GC) remains largely unknown.

Document Details

Document Type
Pub Defense Publication
Publication Date
Nov 05, 2020
Source ID
10.1186/s12943-020-01270-x

Entities

People

  • Duochen Jin
  • Guoxin Zhang
  • Huaiming Sang
  • Lei Peng
  • Shuchun Wei
  • Xuan Li
  • Xudong Zhu
  • Yini Dang
  • Yuanyuan Li

Organizations

  • National Natural Science Foundation of China

Tags

Fields of Study

  • Biology

Readers

  • Molecular Genetics
  • Oncology (Cancer Research).
  • Prostate Cancer Biology.