Repeated closed-head mild traumatic brain injury-induced inflammation is associated with nociceptive sensitization
Abstract
Individuals who have experienced mild traumatic brain injuries (mTBIs) suffer from several comorbidities, including chronic pain. Despite extensive studies investigating the underlying mechanisms of mTBI-associated chronic pain, the role of inflammation in long-term pain after mTBIs is not fully elucidated. Given the shifting dynamics of inflammation, it is important to understand the spatial-longitudinal changes in inflammatory processes following mTBIs and their effects on TBI-related pain.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 27, 2023
- Source ID
- 10.1186/s12974-023-02871-1
Entities
People
- Alexander G. Obukhov
- Andrew Brumett
- Ashlyn G. Cochran
- Edward M. Campbell
- Fletcher A. White
- Jared A. Smith
- Mohammed Al-juboori
- Natalie Nguyen
- Saahil Saxena
- Sarah Talley
- Tyler Nguyen
Organizations
- Congressionally Directed Medical Research Programs
- Indiana Clinical and Translational Sciences Institute