cPLA2 blockade attenuates S100A7-mediated breast tumorigenicity by inhibiting the immunosuppressive tumor microenvironment
Abstract
Molecular mechanisms underlying inflammation-associated breast tumor growth are poorly studied. S100A7, a pro-inflammatory molecule has been shown to enhance breast cancer growth and metastasis. However, the S100A7-mediated molecular mechanisms in enhancing tumor growth and metastasis are unclear.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 08, 2022
- Source ID
- 10.1186/s13046-021-02221-0
Entities
People
- Ajeet K. Verma
- Anum Khan
- Ayush Arpit Garg
- Dinesh K. Ahirwar
- Jalal Siddiqui
- Jonathan W. Song
- Kirti Kaul
- Kunj Vyas
- Manish Charan
- Neety Sahu
- Nidhi Bhutani
- Pranay Agarwal
- Rajni Kant Shukla
- Ramesh K. Ganju
- Sanjay Mishra
- Swati Misri
- Wayne O. Miles
Organizations
- National Institutes of Health
- United States Department of Defense