Lifetime ovulatory years and ovarian cancer gene expression profiles
Abstract
Greater ovulatory years is associated with increased ovarian cancer risk. Although ovulation leads to an acute pro-inflammatory local environment, how long-term exposure to ovulation impacts ovarian carcinogenesis is not fully understood. Thus, we examined the association between gene expression profiles of ovarian tumors and lifetime ovulatory years to enhance understanding of associated biological pathways.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 13, 2022
- Source ID
- 10.1186/s13048-022-00995-1
Entities
People
- Brooke L. Fridley
- Jonathan L Hecht
- Kathryn L. Terry
- Naoko Sasamoto
- Paul A Stewart
- Sean J. Yoder
- Shelley S. Tworoger
- Srikumar Chellappan
- Tianyi Wang
Organizations
- National Institutes of Health
- Rivkin Center for Ovarian Cancer