Local and distant tumor dormancy during early stage breast cancer are associated with the predominance of infiltrating T effector subsets
Abstract
Although breast cancer mortality is a result of distant recurrences associated with the establishment of tumor dormancy, current clinical practice guidelines recommend a wait and watch approach for tumor recurrences. This is because of our limited understanding of tumor dormancy and insufficient evidence in support of immunological control of tumor dormancy.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Oct 28, 2020
- Source ID
- 10.1186/s13058-020-01357-9
Entities
People
- Cara Coleman
- Chunquing Guo
- Georgi Guruli
- Harry D Bear
- Hussein F. Aqbi
- Jennifer Koblinski
- Laura S Graham
- Masoud H Manjili
- Mehran Habibi
- Melika Zarei
- Michael O. Idowu
- Saeed H. Manjili
- Xiang-Yang Wang
- Yibin Xie
Organizations
- National Cancer Institute
- Office of the Secretary of Defense