Body fatness and breast cancer risk in relation to phosphorylated mTOR expression in a sample of predominately Black women
Abstract
The mechanistic target of rapamycin (mTOR) pathway promoted by positive energy imbalance and insulin-like growth factors can be a mechanism by which obesity influences breast cancer risk. We evaluated the associations of body fatness with the risk of breast cancer varied with phosphorylated (p)-mTOR protein expression, an indication of the pathway activation.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 30, 2021
- Source ID
- 10.1186/s13058-021-01458-z
Entities
People
- Angela R. Omilian
- Chi-Chen Hong
- Christine B. Ambrosone
- Elisa V. Bandera
- Rochelle Payne Ondracek
- Song Liu
- Song Yao
- Susmita Datta
- Thaer Khoury
- Ting-Yuan David Cheng
- Warren Davis
- Weizhou Zhang
- Wiam Bshara
Organizations
- National Cancer Institute
- The Breast Cancer Research Foundation
- United States Army Medical Research and Development Command