Gene expression predicts dormant metastatic breast cancer cell phenotype
Abstract
Breast cancer can recur months to decades after an initial diagnosis and treatment. The mechanisms that control tumor cell dormancy remain poorly understood, making it difficult to predict which patients will recur and thus benefit from more rigorous screening and treatments. Unfortunately, the extreme rarity of dormant DTCs has been a major obstacle to their study.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 29, 2022
- Source ID
- 10.1186/s13058-022-01503-5
Entities
People
- Alexander P. Corr
- Peter I. Croucher
- Qihao Ren
- Sheila Stewart
- Tri Giang Phan
- Weng Hua Khoo
Organizations
- National Cancer Institute
- National Institutes of Health
- Office of Research on Women's Health