N6-methyladenosine dynamics in neurodevelopment and aging, and its potential role in Alzheimer’s disease
Abstract
N6-methyladenosine (m6A) modification is known to impact many aspects of RNA metabolism, including mRNA stability and translation, and is highly prevalent in the brain.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 05, 2021
- Source ID
- 10.1186/s13059-020-02249-z
Entities
People
- Andrew M. Shafik
- Bing Yao
- Chuan He
- Emily G. Allen
- Feiran Zhang
- Hao Wu
- Kinga Pajdzik
- Peng Jin
- Qing Dai
- Ranhui Duan
- Yangping Li
- Yunhee Kang
- Zhenxing Guo
Organizations
- National Human Genome Research Institute
- National Institutes of Health
- United States Department of Defense