CRISPR guides induce gene silencing in plants in the absence of Cas
Abstract
RNA-targeting CRISPR-Cas can provide potential advantages over DNA editing, such as avoiding pleiotropic effects of genome editing, providing precise spatiotemporal regulation, and expanded function including antiviral immunity.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 03, 2022
- Source ID
- 10.1186/s13059-021-02586-7
Entities
People
- David Cook
- Divya Mishra
- Geoffrey Preston Morris
- Sandeep Marla
- Tony Jun Huang
- Veerendra Kumar Sharma
- Wei Zhang
- Wenguang Zheng
Organizations
- Defense Advanced Research Projects Agency