A pragmatic randomized trial evaluating pre-operative aqueous antiseptic skin solutions in open fractures (Aqueous-PREP): statistical analysis plan

Abstract

Approximately 1 in 10 patients with a surgically treated open fracture will develop a surgical site infection. The Aqueous-PREP trial will investigate the effect of 10% povidone-iodine versus 4% chlorhexidine in aqueous antiseptic solutions in reducing infections after open fracture surgery. The study protocol was published in April 2020.

Document Details

Document Type
Pub Defense Publication
Publication Date
Sep 12, 2022
Source ID
10.1186/s13063-022-06541-0

Entities

People

  • A. Fidel Moreno
  • A. Stephen Malekzadeh
  • Aaron M. Johnson
  • Abby V. Mcgowan
  • Abigail E. Sagona
  • Ada Mayfield
  • Ahmad Alnasser
  • Albert Soler-cano
  • Aldo Velasco-barrera
  • Alejandra Rojas
  • Alejandro Carballo
  • Alejandro Cruz
  • Alesha N. Scott
  • Alex Burnikel
  • Alexandra Minea
  • Alexandre Berenguer
  • Alfons Gasset-teixidor
  • Alyse Williams
  • Amber Wood
  • Amir Alex Jahangir
  • Amir Matityahu
  • Andrea Howe
  • Andrea Seach
  • Andrew Eglseder
  • Andrew M. Choo
  • Andrew Pollak
  • Andrew W. Cross
  • Anna Alavedra-massana
  • Anna Vergon
  • Annamarie Horan
  • Anthony D. Harris
  • Anthony Ding
  • Anthony T. Sorkin
  • Antoinisha D. English
  • Ariadna Caparros-garcía
  • Ariana Paniagua
  • Ariel Brotherton
  • Arnau Verdaguer-figuerola
  • Arvind G. Von Keudell
  • Arya Amirhekmat
  • Ashley Neese
  • Ashraf El Naga
  • Austin A. Cole
  • Becky Weber
  • Benjamin Judkins
  • Bertrand H. Perey
  • Bill Ristevski
  • Bobbi Clinch
  • Brad Askam
  • Bradley A. Petrisor
  • Brandon Horne
  • Breanna Featherston
  • Brent Bauer
  • Brian H. Mullis
  • C. Daniel Mullins
  • Cameron G. Thomson
  • Carol A. Lin
  • Caroline Benzel
  • Cary C. Schwartzbach
  • Charles N. Moon
  • Charles Pritchett
  • Christian Yela-verdú
  • Christina Boulton
  • Christine Churchill
  • Christopher C. Bray
  • Christopher J. Koenig
  • Christopher Langhammer
  • Christopher Lebrun
  • Christopher M. Domes
  • Christopher T Lee
  • Courteney L. Fentz
  • Dale Williams
  • Daniel J. Stinner
  • Darius G. Viskontas
  • David E. Lazarus
  • David L. Rothberg
  • David Martí-garín
  • David Pogorzelski
  • David Potter
  • David Shearer
  • David W. Lhowe
  • Debra L. Sietsema
  • Debra Marvel
  • Denice M. Dubuclet
  • Derek Donegan
  • Devin S. Mullin
  • Diane Heels-ansdell
  • Dmitry Pokhvashchev
  • Dory S. Boyer
  • Eben A. Carroll
  • Eldrin L. Bhanat
  • Eleni Berhaneselase
  • Elizabeth Lossada-soto
  • Ella Spicer
  • Elsa Rodriguez
  • Emily E Bray
  • Emma W. Denari
  • Eric Hempen
  • Eric Kettering
  • Erin R. Pichiotino
  • Ernesto Guerra-farfán
  • Estrella Sánchez-palomino
  • Ethan J. Maltz
  • Farhad O. Moola
  • Felipe Moreira-borim
  • Ferran Fillat-gomà
  • Franca Mossuto
  • Frances Grissom
  • Francesc Acerboni-flores
  • Francesc Marcano-fernández
  • Genevieve Polk
  • Geoffrey S. Marecek
  • George V. Russell
  • Gerard P Slobogean
  • Gina Del Fabbro
  • Gordon Guyatt
  • Greg E. Gaski
  • Gregory J. Della Rocca
  • Gregory K. Faucher
  • H. Michael Lemke
  • Haley K. Demyanovich
  • Harper Abbott
  • Heather A. Vallier
  • Heather Phipps
  • Heber Enrique Cueva-sevieri
  • Henry Claude Sagi
  • Herman Johal
  • Holly Pilson
  • I Leah Gitajn
  • Iliana Romero
  • Indresh Venkatarayappa
  • Isaac Zarif
  • J. Brett Goodman
  • Ja Nell Dupree
  • Jamal Al-asiri
  • James M. Miller
  • James R. Learned
  • James S. Ahn
  • Jan P. Szatkowski
  • Jana Palmer
  • Jaslynn A. N. Cuff
  • Jason J. Halvorson
  • Jason Lowe
  • Jason Nascone
  • Jaume Cámara-cabrera
  • Jaume Mestre-torres
  • Jean-claude D’alleyrand
  • Jeff E. Schulman
  • Jeff Friedrich
  • Jeffrey Wells
  • Jenna Blasman
  • Jennifer E. Hagen
  • Jennifer Jerele
  • Jennifer Tangtiphaiboontana
  • Jeremy Wise
  • Jessica C. Rivera
  • Joan Hebden
  • Joan Minguell-monyart
  • Joanne Fraifogl
  • Jodi Gallant
  • Joel Sánchez-fernández
  • John A. Scolaro
  • John D. Adams
  • John D. Wyrick
  • John G. Esposito
  • John L. Sanders
  • John Morellato
  • John T. Ruth
  • John W. Munz
  • Jonah Davies
  • Jonathan Wills
  • Jordi Selga-marsa
  • Jordi Teixidor-serra
  • Jordi Tomas-hernandez
  • Jorge Blasco-moreu
  • Jorge Nuñez-camarena
  • Jorge Serrano-sanz
  • Jose Vicente Andres-peiro
  • Josep Rodoreda-puigdemasa
  • Joseph Hsu
  • Joseph P Patterson
  • Joshua Eskew
  • Joshua L. Gary
  • Jothi Murali
  • Juan Antonio Porcel-vazquez
  • Juan Manuel Peñalver
  • Julia C. Quirion
  • Juliette Sweeney
  • Justin Fowler
  • Justin M. Haller
  • Kaitlyn Pusztai
  • Karen Trochez
  • Katelyn M. Garst
  • Kelly L. Apostle
  • Kevin Dwyer
  • Kevin Murphy
  • Kevin Phelps
  • Kimberly Hasselfeld
  • Krishan Rajaratnam
  • Krista Brown
  • Kristi Atkins
  • Kyle J. Jeray
  • Kyle M. Altman
  • Kyrsten Payne
  • L. Edwin Rudisill Jr.
  • Laia Martínez-carreres
  • Lauren C. Hill
  • Laurence B. Kempton
  • Lehana Thabane
  • Linda Clark
  • Lucas S. Marchand
  • Luke A. Lopas
  • Lyndsay M. O'hara
  • M. Christian Moody
  • M. Jason Palmer
  • Madhav Karunakar
  • Manish Sethi
  • Manjari G. Joshi
  • Marcus Coe
  • Marcus Sciadini
  • Maria Del Mar Villar-casares
  • Maria Herrera
  • Maricela M. Diaz
  • Marilyn Heng
  • Marissa Pazik
  • Mark S. Vrahas
  • Markus F. Loeffler
  • Marta Martínez-álvarez
  • Martha B. Holden
  • Mary Dooley
  • Marybeth Horodyski
  • Matilde Molina-corbacho
  • Matsuyama Sanz-molero
  • Matthew Denkers
  • Matthew L. Anderson
  • Matthew L. Graves
  • Matthew Patrick
  • Max Talbot
  • Meir Marmor
  • Mercedes Bueno-ruiz
  • Michael A. Holzman
  • Michael Bosse
  • Michael Colello
  • Michael D McKee
  • Michael J. Beltran
  • Michael J. Gardner
  • Michael J. Weaver
  • Michael Kutzler
  • Michael L. Beckish
  • Michael Prayson
  • Michael S. Sridhar
  • Michael T. Archdeacon
  • Michael Talerico
  • Michelle Medeiros
  • Milton L. “chip” Routt
  • Milton T. Little
  • Mitchel B. Harris
  • Mohit Bhandari
  • Monica Taljaard
  • Morgan K. Dauk
  • Mònica Salomó Domènech
  • Natalie Hogan
  • Nathan N. O’hara
  • Neus Anglada-torres
  • Nicholas M. Romeo
  • Niloofar Dehghan
  • Nirmen Mahal
  • Nuria Gimeno-calavia
  • Núria Fernández-poch
  • Olivia Paige Szasz
  • On Behalf Of The Prep-it Investigators
  • Ona Ràfols-perramon
  • P. J. Devereaux
  • Patricia Martínez-grau
  • Patrick F. Bergin
  • Patrick Osborn
  • Paul Toogood
  • Paula Mckay
  • Philip K. Lim
  • Phillip Mitchell
  • Pilar Lalueza-broto
  • Priyanka Nehete
  • R. Trigg Mcclellan
  • Rachel B Seymour
  • Rachel M. Reilly
  • Rajinder Khanna
  • Ramona Garcia-rodriguez
  • Raymond Pensy
  • Raúl Pellejero-garcía
  • Rebecca G. Snider
  • Richard T. Laughlin
  • Richard Vlasak
  • Richard W. Gurich Jr.
  • Robert A. Hymes
  • Robert Beer
  • Robert Boyce
  • Robert V. O'toole
  • Robert Vandemark Iii
  • Robert Zura
  • Robin Carlson
  • Roman M Natoli
  • Ruben Fuentes-lópez
  • Russell J. Stewart
  • Ryan J. Warth
  • S. John Millon
  • Saam Morshed
  • Samir Mehta
  • Santiago Garcia-gimenez
  • Sara Renaud
  • Sarah Macrae
  • Sarah Pierrie
  • Scott E. Porter
  • Sean Meredith
  • Shannon Dodds
  • Sharmistha Das
  • Sharon Babcock
  • Sheila Sprague
  • Sheketha L. Mcgee
  • Silvia Li
  • Sofia Bzovsky
  • Sophia Hill
  • Stephanie L Tanner
  • Stephen J. Warner
  • Stephen Liang
  • Stephen Sims
  • Sterling Boutte
  • Steven F. Shannon
  • Susan Demas
  • T. Bennett Ramsey
  • Tayler Dykes
  • Taylor Hill
  • Theodore Miclau
  • Theodore Toan Le
  • Theresa A. Chockbengboun
  • Thomas F. Higgins
  • Thomas Krupko
  • Thomas M. Schaller
  • Tigist Belaye
  • Timothy Dew
  • Timothy R. Brown
  • Timothy S. Achor
  • Todd Jaeblon
  • Todd O McKinley
  • Trevor B. Stone
  • Ugur Yener
  • Vicente Molero-garcia
  • Vito Andriola
  • Walter W. Virkus
  • Wendy Williams
  • Wesley Parker
  • William T. Obremskey
  • Xavier Pelfort
  • Yaiza Garcia-sanchez
  • Yan Marco Dela Cruz
  • Yasmin Degani
  • Yeray Maldonado-sotoca
  • Yohan Jang
  • Zachary M. Olsen

Organizations

  • Canadian Institutes of Health Research
  • McMaster University
  • United States Department of Defense

Tags

Fields of Study

  • Medicine

Readers

  • Materials Science (Mechanical Engineering).
  • Trauma Surgery or Emergency Medicine.