Accumulation of copy number alterations and clinical progression across advanced prostate cancer
Abstract
Genomic copy number alterations commonly occur in prostate cancer and are one measure of genomic instability. The clinical implication of copy number change in advanced prostate cancer, which defines a wide spectrum of disease from high-risk localised to metastatic, is unknown.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Sep 05, 2022
- Source ID
- 10.1186/s13073-022-01080-4
Entities
People
- A. M. Mahedi Hasan
- Adnan Ali
- Aine Haran
- Alex Hoyle
- Alex Landless
- Anis A Hamid
- Anna Wingate
- Carla Bautista
- Christopher Brawley
- Christopher J. Sweeney
- Claire Gilson
- Daniel M. Berney
- Daniel Wetterskog
- Emily Grist
- Gerhardt Attard
- Karolina Nowakowska
- Larissa Mendes
- Leila Zakka
- Louise C. Brown
- Mahesh K. B. Parmar
- Malissa Richmond
- Marina Parry
- Matthew R Sydes
- Nafisah B. Akato
- Nicholas D. James
- Nik Matthews
- Noel W. Clarke
- Paolo Cremaschi
- Sharanpreet Lall
- Sofeya Ishaq
- Stampede Investigators
- Stefanie Friedrich
- Stefano Lise
Organizations
- Cancer Research UK
- Defense Advanced Research Projects Agency
- Medical Research Council
- National Institute for Health and Care Research
- National Institutes of Health
- Prostate Cancer Foundation
- Prostate Cancer UK