Defining minimal detectable difference in echocardiographic measures of right ventricular function in systemic sclerosis

Abstract

Echocardiography (2DE) is integral for screening and longitudinal evaluation of pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc). In the present study, we sought to establish the reliability, repeatability, and reproducibility of 2DE parameters in SSc patients with and without PAH and to define the minimal detectable difference (MDD), the smallest change detected beyond measurement error.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jun 18, 2022
Source ID
10.1186/s13075-022-02835-5

Entities

People

  • Ami A Shah
  • Aparna Balasubramanian
  • Catherine E. Simpson
  • Monica Mukherjee
  • Paul M. Hassoun
  • Rachel Damico
  • Stephen C. Mathai
  • Steven Hsu
  • Todd M. Kolb
  • Valentina Mercurio

Organizations

  • Johns Hopkins University
  • MSD (United Kingdom)
  • National Heart, Lung, and Blood Institute
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases
  • Scleroderma Foundation
  • United States Department of Defense

Tags

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Medical Imaging.
  • Systems Analysis and Design