Assessing clinicopathological correlation in chronic traumatic encephalopathy: rationale and methods for the UNITE study

Abstract

Chronic traumatic encephalopathy (CTE) is a progressive neurodegeneration associated with repetitive head impacts. Understanding Neurologic Injury and Traumatic Encephalopathy (UNITE) is a U01 project recently funded by the National Institute of Neurological Disorders and Stroke and the National Institute of Biomedical Imaging and Bioengineering. The goal of the UNITE project is to examine the neuropathology and clinical presentation of brain donors designated as “at risk” for the development of CTE based on prior athletic or military exposure. Here, we present the rationale and methodology for UNITE.

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 12, 2015
Source ID
10.1186/s13195-015-0148-8

Entities

People

  • Alexandra P. Bourlas
  • Ann C. Mckee
  • Bobak Abdolmohammadi
  • Brent M. Ardaugh
  • Brett R. Martin
  • Brian Fry
  • Christine Chaisson
  • Christopher J. Nowinski
  • Daniel H Daneshvar
  • Diane Dixon
  • Douglas I. Katz
  • Jason W. Adams
  • Jesse Mez
  • Joshua Kriegel
  • Katharine J. Babcock
  • Lauren Murphy
  • Lee E. Goldstein
  • Lisa Mchale
  • Neil W. Kowall
  • Patrick T. Kiernan
  • Philip H. Montenigro
  • Robert A. Stern
  • Robert C. Cantu
  • Thor D Stein
  • Todd M. Solomon
  • Victor E. Alvarez
  • Yorghos Tripodis
  • Zachary Papadopoulos

Organizations

  • National Institute of Neurological Disorders and Stroke
  • National Institute on Aging
  • National Operating Committee on Standards for Athletic Equipment
  • United States Department of Defense
  • United States Department of Veterans Affairs

Tags

Fields of Study

  • Medicine
  • Psychology

Readers

  • Defense Technology Research and Development.
  • Neurotrauma and Rehabilitation Medicine.

Technology Areas

  • Biotechnology