Impact of multisession 40Hz tACS on hippocampal perfusion in patients with Alzheimer’s disease

Abstract

Alzheimer’s disease (AD) is associated with alterations in cortical perfusion that correlate with cognitive impairment. Recently, neural activity in the gamma band has been identified as a driver of arteriolar vasomotion while, on the other hand, gamma activity induction on preclinical models of AD has been shown to promote protein clearance and cognitive protection.

Document Details

Document Type
Pub Defense Publication
Publication Date
Dec 01, 2021
Source ID
10.1186/s13195-021-00922-4

Entities

People

  • Alvaro Pascual Leone
  • Ann Connor
  • Daniel Press
  • David C. Alsop
  • Davide Cappon
  • Emiliano Santarnecchi
  • Fanny Munsch
  • Georges El Fakhri
  • Giulia Sprugnoli
  • Giulio Ruffini
  • Joanna Macone
  • Kevin Donohoe
  • Mouhsin M. Shafi
  • Rachel Paciorek
  • Ricardo Salvador

Organizations

  • Beth Israel Deaconess Medical Center
  • Defense Advanced Research Projects Agency

Tags

Fields of Study

  • Biology
  • Medicine
  • Psychology

Readers

  • Cardiovascular Physiology
  • Neuroscience