A comparison between tau and amyloid-β cerebrospinal fluid biomarkers in chronic traumatic encephalopathy and Alzheimer disease

Abstract

Cerebrospinal fluid (CSF) tau and beta-amyloid levels in chronic traumatic encephalopathy (CTE), a disease which can be clinically indistinguishable from Alzheimer’s disease (AD), are largely unknown. We examined postmortem CSF analytes among participants with autopsy confirmed CTE and AD.

Document Details

Document Type
Pub Defense Publication
Publication Date
Feb 09, 2022
Source ID
10.1186/s13195-022-00976-y

Entities

People

  • Alexandra Geada
  • Andrew E. Budson
  • Ann C. Mckee
  • Bertrand R. Huber
  • Brigid Dwyer
  • Douglas I. Katz
  • Gaoyuan Meng
  • Jesse Mez
  • Jonathan D Cherry
  • Katherine W. Turk
  • Lee E. Goldstein
  • Michael L Alosco
  • Neil W. Kowall
  • Raymond Nicks
  • Robert A. Stern
  • Robert C. Cantu
  • Sarah Daley
  • Thor D Stein
  • Victor E. Alvarez
  • Weiming Xia
  • Yorghos Tripodis

Organizations

  • Alzheimer's Association
  • National Heart, Lung, and Blood Institute
  • National Institute of Neurological Disorders and Stroke
  • National Institute on Aging
  • United States Department of Defense
  • United States Department of Veterans Affairs

Tags

Fields of Study

  • Biology
  • Medicine

Readers

  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.