Detecting heterogeneity in and between breast cancer cell lines
Abstract
Cellular heterogeneity in tumor cells is a well-established phenomenon. Genetic and phenotypic cell-to-cell variability have been observed in numerous studies both within the same type of cancer cells and across different types of cancers. Another known fact for metastatic tumor cells is that they tend to be softer than their normal or non-metastatic counterparts. However, the heterogeneity of mechanical properties in tumor cells are not widely studied.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 03, 2020
- Source ID
- 10.1186/s41236-020-0010-1
Entities
People
- B. U. Sebastian Schmidt
- Benjamin Wolf
- Erik W. Morawetz
- Hans Kubitschke
- Josef A. Käs
- Wolfgang Losert
- Yang Shen
Organizations
- Air Force Office of Scientific Research
- European Research Council
- Horizon 2020