High frequency alternating current neurostimulation decreases nocifensive behavior in a disc herniation model of lumbar radiculopathy

Abstract

The purpose of this study was to evaluate if kilohertz frequency alternating current (KHFAC) stimulation of peripheral nerve could serve as a treatment for lumbar radiculopathy. Prior work shows that KHFAC stimulation can treat sciatica resulting from chronic sciatic nerve constriction. Here, we evaluate if KHFAC stimulation is also beneficial in a more physiologic model of low back pain which mimics nucleus pulposus (NP) impingement of a lumbar dorsal root ganglion (DRG).

Document Details

Document Type
Pub Defense Publication
Publication Date
Jul 12, 2023
Source ID
10.1186/s42234-023-00119-0

Entities

People

  • Ken Porche
  • Kevin J Otto
  • Kyle D. Allen
  • Lauren Savannah Dewberry
  • Travis Koenig

Organizations

  • National Institute of Arthritis and Musculoskeletal and Skin Diseases
  • National Science Foundation

Tags

Fields of Study

  • Medicine

Readers

  • Electrical Engineering
  • Neuroscience
  • Neurotrauma and Rehabilitation Medicine.