ATP release and autocrine signaling through P2X4 receptors regulate γδ T cell activation

Abstract

Circulating human γδ T cells release ATP upon in vitro stimulation, which signals through P2X4 receptors and governs these cellsˈ function.

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 01, 2012
Source ID
10.1189/jlb.0312121

Entities

People

  • Anjali A Karande
  • Mark I Hirsh
  • Monali Manohar
  • Tobias Woehrle
  • Wolfgang G. Junger
  • Yu Chen

Organizations

  • Congressionally Directed Medical Research Programs
  • Harvard Medical School
  • Indian Institute of Science, Bengaluru
  • National Institutes of Health

Tags

Fields of Study

  • Biology
  • Medicine

Readers

  • Oncology (Cancer Research).