Optochiasmatic Arachnoiditis with Treatment by Surgical Lysis of Adhesions, Corticosteroids, and Cyclophosphamide: Report of a Case

Abstract

A 24-year-old woman presented with progressive optochiasmatic arachnoiditis causing progressively worsening visual loss associated with headache and amenorrhea. Treatment with the standard initial therapy of dexamethasone, warfarin, and dipyridamole was unsuccessful at halting her disease process. Surgical lysis of adhesions led to a temporary improvement and then deterioration. A course of therapy with cyclophosphamide was initiated and her response to this therapy resulted in resolution of her headaches, return of her vision to normal, and resumption of her normal menstrual cycles.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jul 01, 1986
Source ID
10.1227/00006123-198607000-00015

Entities

People

  • Alan O. Marcus
  • Daniel S. Duick
  • H. Arlene Ross
  • John J. Demakas
  • Robert M. Crowell

Organizations

  • St. Joseph's Hospital and Medical Center
  • United States Navy
  • University of Illinois Urbana–Champaign
  • University of Southern California

Tags

Fields of Study

  • Medicine

Readers

  • Neurotrauma and Rehabilitation Medicine.
  • Oncology (Cancer Research).
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.