Comparison of transcriptional responses between pathogenic and nonpathogenic hantavirus infections in Syrian hamsters using NanoString
Abstract
Syrian hamsters infected with Andes virus (ANDV) develop a disease that recapitulates many of the salient features of human hantavirus pulmonary syndrome (HPS), including lethality. Infection of hamsters with Hantaan virus (HTNV) results in an asymptomatic, disseminated infection. In order to explore this dichotomy, we examined the transcriptome of ANDV- and HTNV-infected hamsters.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 02, 2021
- Source ID
- 10.1371/journal.pntd.0009592
Entities
People
- Brian D Carey
- Candace D. Blancett
- Casey C. Perley
- Jay W. Hooper
- Louis A Altamura
- Rebecca Brocato
- Timothy D Minogue
Organizations
- Defense Threat Reduction Agency