Whole-genome sequencing and genetic diversity of severe fever with thrombocytopenia syndrome virus using multiplex PCR-based nanopore sequencing, Republic of Korea

Abstract

Whole-genome sequencing plays a critical role in the genomic epidemiology intended to improve understanding the spread of emerging viruses. Dabie bandavirus, causing severe fever with thrombocytopenia syndrome (SFTS), is a zoonotic tick-borne virus that poses a significant public health threat. We aimed to evaluate a novel amplicon-based nanopore sequencing tool to obtain whole-genome sequences of Dabie bandavirus, also known as SFTS virus (SFTSV), and investigate the molecular prevalence in wild ticks, Republic of Korea (ROK).

Document Details

Document Type
Pub Defense Publication
Publication Date
Sep 12, 2022
Source ID
10.1371/journal.pntd.0010763

Entities

People

  • Daesang Lee
  • Dong-hyun Song
  • Geum-young Lee
  • Gyeung Haeng Hur
  • Heung-Chul Kim
  • Hyeong Seok Yun
  • Il-ung Hwang
  • Jeewan Choi
  • Jeong-ah Kim
  • Jingyeong Lee
  • Jongwoo Kim
  • Jung-Eun Kim
  • Juwan Park
  • Kyungmin Park
  • Se Hun Gu
  • Seong Tae Jeong
  • Seung-ho Lee
  • Seungchan Cho
  • Terry A. Klein
  • Won-Keun Kim

Organizations

  • Agency for Defense Development
  • Armed Forces Health Surveillance Center
  • Institute for Basic Science
  • Ministry of Education of the Republic of Korea

Tags

Fields of Study

  • Biology

Readers

  • Infectious Disease/Epidemiology
  • Molecular and genetic basis of cancer.

Technology Areas

  • Biotechnology