A spontaneous mutation in kdsD, a biosynthesis gene for 3 Deoxy-D-manno-Octulosonic Acid, occurred in a ciprofloxacin resistant strain of Francisella tularensis and caused a high level of attenuation in murine models of tularemia

Document Details

Document Type
Pub Defense Publication
Publication Date
Mar 22, 2017
Source ID
10.1371/journal.pone.0174106

Entities

People

  • Christopher K Cote
  • Fabrice V. Biot
  • Galina Koroleva
  • Gustavo Palacios
  • Jason T. Ladner
  • Jennifer Chua
  • Jo Lynne Raymond
  • Joel A. Bozue
  • Jonathan E. Nuss
  • Lynda Miller
  • Nicholas J. Vietri
  • Patricia L. Worsham
  • Ronald G. Toothman
  • Samandra Demons
  • Sean Lovett
  • Sherry Mou
  • Stephanie Halasohoris
  • Taylor Chance
  • Todd M. Kijek

Organizations

  • Defense Threat Reduction Agency