Distal organ inflammation and injury after resuscitative endovascular balloon occlusion of the aorta in a porcine model of severe hemorrhagic shock
Abstract
Resuscitative Endovascular Balloon Occlusion of Aorta (REBOA) has emerged as a potential life-saving maneuver for the management of non-compressible torso hemorrhage in trauma patients. Complete REBOA (cREBOA) is inherently associated with the burden of ischemia reperfusion injury (IRI) and organ dysfunction. However, the distal organ inflammation and its association with organ injury have been little investigated. This study was conducted to assess these adverse effects of cREBOA following massive hemorrhage in swine.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Nov 17, 2020
- Source ID
- 10.1371/journal.pone.0242450
Entities
People
- Andriy I. Batchinsky
- Brandon J. Gremmer
- Bryan S. Jordan
- Corina Necsoiu
- Johnny L. Barr
- Leopoldo C. Cancio
- Michael A. Dubick
- Michael L. Lucas
- Yansong Li
- Zhangsheng Yang
Organizations
- United States Army Medical Research and Development Command