Early detection of neutralizing antibodies against SARS-CoV-2 in COVID-19 patients in Thailand
Abstract
The presence of neutralizing antibodies (NAbs) is an indicator of protective immunity for most viral infections. A newly developed surrogate viral neutralization assay (sVNT) offers the ability to detect total receptor binding domain-targeting NAbs in an isotype-independent manner, increasing the test sensitivity. Thus, specimens with low IgM/ IgG antibody levels showed strong neutralization activity in sVNT.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 12, 2021
- Source ID
- 10.1371/journal.pone.0246864
Entities
People
- Chanida Ruchisrisarod
- Chee Wah Tan
- Gompol Suwanpimolkul
- Jiratchaya Sophonphan
- Leilani Paitoonpong
- Lin-Fa Wang
- Opass Putcharoen
- Pajaree Chariyavilaskul
- Phanni Wanthong
- Supaporn Wacharapluesadee
- Thiravat Hemachudha
- Wan Ni Chia
- Watsamon Jantarabenjakul
Organizations
- Defense Threat Reduction Agency
- Duke Energy
- King Chulalongkorn Memorial Hospital
- Yale-NUS