A fiber optic–nanophotonic approach to the detection of antibodies and viral particles of COVID-19
Abstract
Dr. Deborah Birx, the White House Coronavirus Task Force coordinator, told NBC News on “Meet the Press” that “[T]he U.S. needs a ‘breakthrough’ in coronavirus testing to help screen Americans and get a more accurate picture of the virus’ spread.” We have been involved with biopathogen detection since the 2001 anthrax attacks and were the first to detect anthrax in real-time. A variation on the laser spectroscopic techniques we developed for the rapid detection of anthrax can be applied to detect the Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2 virus). In addition to detecting a single virus, this technique allows us to read its surface protein structure. In particular, we have been conducting research based on a variety of quantum optical approaches aimed at improving our ability to detect Corona Virus Disease-2019 (COVID-19) viral infection. Indeed, the detection of a small concentration of antibodies, after an infection has passed, is a challenging problem. Likewise, the early detection of disease, even before a detectible antibody population has been established, is very important. Our team is researching both aspects of this problem. The paper is written to stimulate the interest of both physical and biological scientists in this important problem. It is thus written as a combination of tutorial (review) and future work (preview). We join Prof. Federico Capasso and Editor Dennis Couwenberg in expressing our appreciation to all those working so heroically on all aspects of the COVID-19 problem. And we thank Drs. Capasso and Couwenberg for their invitation to write this paper.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Sep 29, 2020
- Source ID
- 10.1515/nanoph-2020-0357
Entities
People
- Aart Verhoef
- Aleksei Zheltikov
- Alexei Sokolov
- Alma Fernández-gonzález
- Anatoly A. Svidzinsky
- Benjamin W. Neuman
- Chao-Yang Lu
- Da-Wei Wang
- Edward Fry
- G. S. Agarwal
- Garry Adams
- George Kattawar
- Jeffrey Cirillo
- Jon Mogford
- Kai Wang
- Kimberly Chapin
- Lan Yang
- Marlan Scully
- Ming-che Lee
- Moochan Kim
- Navid Rajil
- Pan Jianwei
- Philip Hemmer
- Robert Brick
- S. Suckewer
- Sahar Delfan
- Shahriar Esmaeili
- Shi-Yao Zhu
- Steven Scully
- Suhail Zubairy
- Tao Peng
- Vincent Poor
- Volker Deckert
- Vsevolod Belousov
- Yanhua Shih
- Zehua Han
- Zhenhuan Yi
Organizations
- Air Force Office of Scientific Research
- Baylor University
- Collins Aerospace
- Friedrich Schiller University Jena
- King Abdulaziz City for Science and Technology
- Leibniz Institute of Photonic Technology
- Moscow State University
- National Institutes of Health
- National Science Foundation
- Office of Naval Research
- Princeton University
- Robert A. Welch Foundation
- Russian Academy of Sciences
- Russian National Research Medical University
- Russian Quantum Center
- Texas A&M University
- Texas A&M University System
- University of Maryland, Baltimore County
- University of Science and Technology of China
- Washington University in St. Louis
- Zhejiang University