Acute Bacterial Osteoarticular Infections: Eight-Year Analysis of C-Reactive Protein for Oral Step-Down Therapy
Abstract
One of the most important decisions in the treatment of osteoarticular infections is the time at which parenteral therapy can be changed to oral therapy. C-reactive protein (CRP) is an acute inflammatory indicator with a half-life of 19 hours and thus can be helpful in assessing the adequacy of therapy for bacterial infections. At our institution, a combination of CRP and clinical findings is used to determine the transition to oral therapy.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Oct 01, 2012
- Source ID
- 10.1542/peds.2012-0220
Entities
People
- Ben Westley
- Christopher R. Cannavino
- John Bradley
- John C. Arnold
- Mindy K. Ross
- Robert H. Riffenburgh
- Thomas C. Miller
Organizations
- Brown University
- Naval Medical Center San Diego
- University of California, San Diego