Autophagy and Apoptosis Specific Knowledgebases-guided Systems Pharmacology Drug Research
Abstract
Autophagy and apoptosis are the basic physiological processes in cells that clean up aged and mutant cellular components or even the entire cells. Both autophagy and apoptosis are disrupted in most major diseases such as cancer and neurological disorders. Recently, increasing attention has been paid to understand the crosstalk between autophagy and apoptosis due to their tightly synergetic or opposite functions in several pathological processes.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 20, 2019
- Source ID
- 10.2174/1568009619666190206122149
Entities
People
- Lirong Wang
- Nanyi Wang
- Peihao Fan
- Xiang-Qun Xie
Organizations
- National Institute on Drug Abuse
- United States Department of Defense
- University of Pittsburgh