Rapid Nucleic Acid Reaction Circuits for Point-of-care Diagnosis of Diseases
Abstract
An urgent need exists for a rapid, cost-effective, facile, and reliable nucleic acid assay for mass screening to control and prevent the spread of emerging pandemic diseases. This urgent need is not fully met by current diagnostic tools. In this review, we summarize the current state-of-the-art research in novel nucleic acid amplification and detection that could be applied to point-of-care (POC) diagnosis and mass screening of diseases. The critical technological breakthroughs will be discussed for their advantages and disadvantages. Finally, we will discuss the future challenges of developing nucleic acid-based POC diagnosis.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Mar 01, 2022
- Source ID
- 10.2174/1570163819666220207114148
Entities
People
- Anthony Monte Carlo
- Catherine Grgicak
- Doris Zheng
- Emily Guan
- Ezry Santiago-McRae
- Jinglin Fu
- Omri Bar
- Sung Won Oh
Organizations
- High Technology High School
- Rutgers University
- Rutgers University–Camden
- United States Department of Defense