Analysis of Stable Chelate-free Gadolinium Loaded Titanium Dioxide Nanoparticles for MRI-Guided Radionuclide Stimulated Cancer Treatment

Abstract

Recent studies demonstrate that titanium dioxide nanoparticles (TiO2 NPs) are an effective source of reactive oxygen species (ROS) for photodynamic therapy and radionuclide stimulated dynamic therapy (RaST). Unfortunately, tracking the in vivo distribution of TiO2 NPs noninvasively remains elusive.

Document Details

Document Type
Pub Defense Publication
Publication Date
Aug 01, 2022
Source ID
10.2174/1573411018666220321102736

Entities

People

  • Brad Manion
  • Duanwen Shen
  • Gail P. Sudlow
  • Hengbo Huang
  • James D. Quirk
  • Jie Zheng
  • Lei Fang
  • Matthew Mixdorf
  • Partha Karmakar
  • Rui Tang
  • Samuel Achilefu

Organizations

  • Cancer Prevention and Research Institute of Texas
  • National Institutes of Health
  • United States Department of Defense
  • University of Texas Southwestern Medical Center
  • Washington University in St. Louis

Tags

Readers

  • Medical Imaging.
  • Surface Engineering/Surface Coating Technology.

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech