Evidence of increased brain amyloid in severe TBI survivors at 1, 12, and 24 months after injury: report of 2 cases
Abstract
Traumatic brain injury (TBI) is a major risk factor for Alzheimer’s disease. With respect to amyloid deposition, there are no published serial data regarding the deposition rate of amyloid throughout the brain after TBI. The authors conducted serial 18F-AV-45 (florbetapir F18) positron emission tomography (PET) imaging in 2 patients with severe TBI at 1, 12, and 24 months after injury. A total of 12 brain regions were surveyed for changes in amyloid levels.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jun 01, 2016
- Source ID
- 10.3171/2015.6.jns15639
Entities
People
- Cari Stebbins
- Christopher Madden
- Dana Mathews
- Hunt Batjer
- Joseph P. Minei
- Joshua W. Gatson
- Ramon Diaz-Arrastia
- Thomas S. Harris
Organizations
- Uniformed Services University of the Health Sciences
- University of Texas at Austin