Survival and invasiveness of astrocytomas promoted by erythropoietin
Abstract
The hypoxia-inducible pleiotropic hormone, erythropoietin (EPO), has recently been found to promote the development and survival of neurons and astrocytes. Since hypoxia has been implicated in the malignant progression of some human cancers, the authors investigated whether EPO signaling influenced the malignant properties of human astrocytoma cells.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 01, 2007
- Source ID
- 10.3171/jns.2007.106.2.338
Entities
People
- A. Sasha Tait
- Ahmed Mohyeldin
- Ajay Verma
- Clifton L Dalgard
- Elizabeth Rushing
- Geza Acs
- Huasheng Lu
- Kondi Wong
- Subhojit Roy
- Thomas Mcfate
- Viral C. Patel
Organizations
- Armed Forces Institute of Pathology
- Uniformed Services University of the Health Sciences
- University of Pennsylvania