Antibodies to Citrullinated Protein Antigens, Rheumatoid Factor Isotypes and the Shared Epitope and the Near-Term Development of Clinically-Apparent Rheumatoid Arthritis
Abstract
In rheumatoid arthritis (RA) autoantibodies including antibodies to citrullinated protein antigens (ACPA) and rheumatoid factor (RF) can be predictive of incident clinical RA. However, there is limited understanding of how antibody changes over time impact prediction of the likelihood and timing of future clinical RA.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jun 22, 2022
- Source ID
- 10.3389/fimmu.2022.916277
Entities
People
- Christopher C. Striebich
- Dylan T. Bergstedt
- Elizabeth A. Bemis
- Geoffrey M. Thiele
- Jess D. Edison
- Jill M. Norris
- Kevin D Deane
- Laurakay Moss
- M Kristen Demoruelle
- Marie L. Feser
- Mark C. Parish
- Ryan A Peterson
- Ted R Mikuls
- V. Michael Holers
- Wyatt J. Tarter
Organizations
- Congressionally Directed Medical Research Programs
- National Institute of Arthritis and Musculoskeletal and Skin Diseases