Spatial biology analysis reveals B cell follicles in secondary lymphoid structures may regulate anti-tumor responses at initial melanoma diagnosis
Abstract
B cells are key regulators of immune responses in melanoma. We aimed to explore differences in the histologic location and activation status of B cell follicles in sentinel lymph nodes (SLN) of melanoma patients.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 15, 2022
- Source ID
- 10.3389/fimmu.2022.952220
Entities
People
- Aaron D. Therien
- David Boczkowski
- Douglas S. Tyler
- Eda K Holl
- Georgia M. Beasley
- Kristen E. Rhodin
- Norma E. Farrow
- Rami N. Al-rohil
- Smita K Nair
Organizations
- National Institutes of Health
- United States Department of Defense