Plasma enzymatic activity, proteomics and peptidomics in COVID-19-induced sepsis: A novel approach for the analysis of hemostasis
Abstract
Introduction: Infection by SARS-CoV-2 and subsequent COVID-19 can cause viral sepsis. We investigated plasma protease activity patterns in COVID-19-induced sepsis with bacterial superinfection, as well as plasma proteomics and peptidomics in order to assess the possible implications of enhanced proteolysis on major protein systems (e.g., coagulation).
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 11, 2023
- Source ID
- 10.3389/fmolb.2022.1051471
Entities
People
- Anthony J. O'Donoghue
- Erik B Kistler
- Federico Aletti
- Fernando dos Santos
- Joyce B Li
- Laura Beretta
- Maria Claudia Irigoyen
- Mazen F. Odish
- Michael T. Y. Lam
- Nathalia Juocys
- Nicole G. Coufal
- Rafi Mazor
Organizations
- California Breast Cancer Research Program