Progressive structural and covariance connectivity abnormalities in patients with Alzheimer’s disease

Abstract

Alzheimer’s disease (AD) is one of most prevalent neurodegenerative diseases worldwide and characterized by cognitive decline and brain structure atrophy. While studies have reported substantial grey matter atrophy related to progression of AD, it remains unclear about brain regions with progressive grey matter atrophy, covariance connectivity, and the associations with cognitive decline in AD patients.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 06, 2023
Source ID
10.3389/fnagi.2022.1064667

Entities

People

  • Jiaojian Wang
  • Kaiyu Huang
  • Lei Gao
  • Shun Yao
  • Yaqiong Xiao

Organizations

  • Alzheimer's Disease Neuroimaging Initiative
  • National Institutes of Health
  • National Natural Science Foundation of China
  • Natural Science Foundation of Yunnan Province

Tags

Fields of Study

  • Psychology

Readers

  • Neurotrauma and Rehabilitation Medicine.
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.