Combined Structural MR and Diffusion Tensor Imaging Classify the Presence of Alzheimer’s Disease With the Same Performance as MR Combined With Amyloid Positron Emission Tomography: A Data Integration Approach
Abstract
Background: In recent years, classification frameworks using imaging data have shown that multimodal classification methods perform favorably over the use of a single imaging modality for the diagnosis of Alzheimer’s Disease. The currently used clinical approach often emphasizes the use of qualitative MRI and/or PET data for clinical diagnosis. Based on the hypothesis that classification of isolated imaging modalities is not predictive of their respective value in combined approaches, we investigate whether the combination of T1 Weighted MRI and diffusion tensor imaging (DTI) can yield an equivalent performance as the combination of quantitative structural MRI (sMRI) with amyloid-PET.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 05, 2022
- Source ID
- 10.3389/fnins.2021.638175
Entities
People
- Ana Paula Moreira
- Antero Abrunhosa
- Daniel Agostinho
- Francisco Caramelo
- Isabel Santana
- Miguel Castelo-branco
Organizations
- Alzheimer's Disease Neuroimaging Initiative
- Fundação para a Ciência e Tecnologia