Development of a computational fluid dynamic model to investigate the hemodynamic impact of REBOA
Abstract
Background: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a lifesaving intervention for major truncal hemorrhage. Balloon-tipped arterial catheters are inserted via the femoral artery to create a temporary occlusion of the aorta, which minimizes the rate of internal bleeding until definitive surgery can be conducted. There is growing concern over the resultant hypoperfusion and potential damage to tissues and organs downstream of REBOA. To better understand the acute hemodynamic changes imposed by REBOA, we developed a three-dimensional computational fluid dynamic (CFD) model under normal, hemorrhage, and aortic occlusion conditions. The goal was to characterize the acute hemodynamic changes and identify regions within the aortic vascular tree susceptible to abnormal flow and shear stress.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Oct 13, 2022
- Source ID
- 10.3389/fphys.2022.1005073
Entities
People
- Antonio C. Renaldo
- Elaheh Rahbar
- F. Scott Gayzik
- Fahim Mobin
- James E. Jordan
- Lucas P. Neff
- Magan R. Lane
- Sophie R. Shapiro
- Timothy K. Williams
Organizations
- Congressionally Directed Medical Research Programs
- National Heart, Lung, and Blood Institute
- National Science Foundation
- United States Army Medical Research and Development Command