Common Data Elements, Scalable Data Management Infrastructure, and Analytics Workflows for Large-Scale Neuroimaging Studies

Abstract

Neuroscience studies require considerable bioinformatic support and expertise. Numerous high-dimensional and multimodal datasets must be preprocessed and integrated to create robust and reproducible analysis pipelines. We describe a common data elements and scalable data management infrastructure that allows multiple analytics workflows to facilitate preprocessing, analysis and sharing of large-scale multi-level data. The process uses the Brain Imaging Data Structure (BIDS) format and supports MRI, fMRI, EEG, clinical, and laboratory data. The infrastructure provides support for other datasets such as Fitbit and flexibility for developers to customize the integration of new types of data. Exemplar results from 200+ participants and 11 different pipelines demonstrate the utility of the infrastructure.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jun 17, 2021
Source ID
10.3389/fpsyt.2021.682495

Entities

People

  • Ahmad Mayeli
  • Brett A. Mckinney
  • James Touthang
  • Jerzy Bodurka
  • Martin P. Paulus
  • Masaya Misaki
  • Neuromap-investigators
  • Obada Al Zoubi
  • Rayus Kuplicki
  • Robin L. Aupperle
  • T. Kent Teague

Organizations

  • National Institute of General Medical Sciences
  • United States Department of Defense
  • William K. Warren Foundation

Tags

Fields of Study

  • Computer science

Readers

  • Defense Technology Research and Development.
  • Neural Network Machine Learning.
  • Systems Analysis and Design