DNA-Directed Assembly of Carbon Nanotube–Protein Hybrids

Abstract

Here, we report the controlled assembly of SWCNT–GFP hybrids employing DNA as a linker. Two distinct, enriched SWCNTs chiralities, (6,5), (7,6), and an unsorted SWCNT solution, were selectively functionalized with DNA and hybridized to a complementary GFPDNA conjugate. Atomic force microscopy images confirmed that GFP attachment occurred predominantly at the terminal ends of the nanotubes, as designed. The electronic coupling of the proteins to the nanotubes was confirmed via in-solution fluorescence spectroscopy, that revealed an increase in the emission intensity of GFP when linked to the CNTs.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jun 29, 2021
Source ID
10.3390/biom11070955

Entities

People

  • D Dafydd Jones
  • Mark Freeley
  • Matteo Palma
  • Rebecca E. A. Gwyther

Organizations

  • Air Force Office of Scientific Research

Tags

Readers

  • Molecular Genetics
  • Nanocomposite Materials Science

Technology Areas

  • Microelectronics