Closed-Loop Controlled Fluid Administration Systems: A Comprehensive Scoping Review

Abstract

Physiological Closed-Loop Controlled systems continue to take a growing part in clinical practice, offering possibilities of providing more accurate, goal-directed care while reducing clinicians’ cognitive and task load. These systems also provide a standardized approach for the clinical management of the patient, leading to a reduction in care variability across multiple dimensions. For fluid management and administration, the advantages of closed-loop technology are clear, especially in conditions that require precise care to improve outcomes, such as peri-operative care, trauma, and acute burn care. Controller design varies from simplistic to complex designs, based on detailed physiological models and adaptive properties that account for inter-patient and intra-patient variability; their maturity level ranges from theoretical models tested in silico to commercially available, FDA-approved products. This comprehensive scoping review was conducted in order to assess the current technological landscape of this field, describe the systems currently available or under development, and suggest further advancements that may unfold in the coming years. Ten distinct systems were identified and discussed.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jul 18, 2022
Source ID
10.3390/jpm12071168

Entities

People

  • David Berard
  • Emily N. Boice
  • Eric J Snider
  • Guy Avital
  • Josè Salinas
  • Saul J. Vega
  • Sofia I. Hernandez Torres
  • Víctor A. Convertino

Organizations

  • United States Army Medical Research and Development Command

Tags

Fields of Study

  • Medicine

Readers

  • Systems Analysis and Design
  • Trauma or Military Medicine