Gelatin-Coated Magnetic Nanowires for High-Sensitivity Optical Labels
Abstract
The encapsulation of magnetic nickel nanowires (NiNWs) with gelatin is proposed as an alternative for optical label detection. Magnetic nanowires can be detected at very low concentrations using light-scattering methods. This detection capacity could be helpful in applications such as transducers for molecular and biomolecular sensors; however, potential applications require the attachment of specific binding molecules to the nanowire structure. In the present study, a method is presented which is helpful in coating magnetic nanowires with gelatin, a material with the potential to handle specific decoration and functionalization of the nanowires; in the first case, silver nanoparticles (AgNPs) are efficiently used to decorate the nanowires. Furthermore, it is shown that the synthesized gelatin-coated particles have excellent detectability to the level of 140 pg/mL; this level of detection outperforms more complex techniques such as ICP-OES (~3 ng/mL for Ni) and magnetoresistance sensing (~10 ng/mL for magnetic nanoparticles).
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 20, 2022
- Source ID
- 10.3390/nano13010015
Entities
People
- Alejandro J. Giménez
- Alejandro Manzano-Ramírez
- Gabriel Luna-Barcenas
- J. Mauricio López-Romero
- M. Charbel Cuevas-corona
- Rodrigo Esparza
- Rosa E. Zavala-arce
Organizations
- Army Research Office