Characteristics and Prevalence of Latent Autoimmune Diabetes in Adults (LADA)

Abstract

Diabetes, one of the most commonly seen metabolic disorders, is affecting a major area of population in many developing as well as most of the developed countries and is becoming an alarming concern for the rising cost of the healthcare system. Latent Autoimmune Diabetes in Adults (LADA) is a form of diabetes which is less recognized and underdiagnosed type of diabetes which appears to have characteristics of bothtype 1(autoimmune in nature) andtype 2 diabetes(adult age at onset and initial response to oral hypoglycemic agents). An epidemiological study was carried out on 500 patients in the western region of India. Various parameters such as age at onset, duration of diabetes, gender, basal metabolic index (BMI), type of diabetes, family history, HbA1c levels, cholesterol levels, and current treatment regimen were evaluated and correlated withtype 1andtype 2 diabetes.Moreover, diagnostic markers for LADA, namely, GAD autoantibodies and C-peptide levels, were determined for 80 patients selected from the epidemiological study. Some of the results obtained were found to be consistent with the literature whereas some results were found to be contradictory to the existing data.

Document Details

Document Type
Pub Defense Publication
Publication Date
Apr 08, 2012
Source ID
10.5402/2012/580202

Entities

People

  • Anita A. Mehta
  • Banshi D. Saboo
  • Priyanka P. Brahmkshatriya
  • Ramesh K. Goyal

Organizations

  • All India Council for Technical Education
  • Gujarat Technological University

Tags

Fields of Study

  • Medicine

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