Delayed‐type hypersensitivity (DTH) test anergy does not impact CD4 reconstitution or normalization of DTH responses during antiretroviral therapy
Abstract
Delayed‐type hypersensitivity (DTH) testing is an in vivo assessment of cell‐mediated immunity. Although highly active antiretroviral therapy (HAART) improves immunologic parameters, the relationship between DTH responsiveness and CD4 gains on HAART is not completely understood. We investigated CD4 reconstitution and the change in DTH responses from treatment baseline through 24 months of viral load (VL)‐suppressive HAART in the U.S. Military HIV Natural History Study.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2014
- Source ID
- 10.7448/ias.17.1.18799
Entities
People
- Brian K. Agan
- Jason F. Okulicz
- Natascha M Minidis
- Octavio Mesner
Organizations
- National Institute of Allergy and Infectious Diseases
- National Institutes of Health
- Uniformed Services University of the Health Sciences