Transcriptional correlates of malaria in RTS,S/AS01-vaccinated African children: a matched case–control study
Abstract
In a phase 3 trial in African infants and children, the RTS,S/AS01 vaccine (GSK) showed moderate efficacy against clinical malaria. We sought to further understand RTS,S/AS01-induced immune responses associated with vaccine protection.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 21, 2022
- Source ID
- 10.7554/elife.70393
Entities
People
- Augusto Nhabomba
- Benjamin Mordmüller
- Carl Muriel
- Carlota Dobaño
- Chenjerai Jairoce
- Clarissa Valim
- Claudia Daubenberger
- Daniel Neafsey
- Gemma Moncunill Piñas
- Greg Finak
- Héctor Sanz
- Jason Carnes
- John J Aponte
- Joseph J Campo
- Julie McElrath
- Kenneth D. Stuart
- Lindsay N Carpp
- Maxmillian Mpina
- Nana Aba Williams
- Núria Díez-padrisa
- Paige Haas
- Phu Van
- Raphael Gottardo
- Selidji T Agnandji
- Sheetij Dutta
- Stephen De Rosa
- William Chad Young
Organizations
- Boston University
- Carlos III Health Institute
- Center for Global Infectious Disease Research
- Fred Hutchinson Cancer Center
- Gates Foundation
- Harvard T.H. Chan School of Public Health
- Institute of Tropical Medicine Antwerp
- Massachusetts Institute of Technology
- Ministry of Health of the Government of Catalonia
- National Institute of Allergy and Infectious Diseases
- Pollita Institute
- Swiss Tropical and Public Health Institute
- University of Basel
- University of Lausanne
- University of Washington
- Walter Reed Army Institute of Research