Biodosimetry (USUHS)
Abstract
For the Uniformed Services University of the Health Sciences/Armed Forces Radiobiology Research Institute (USUHS/AFRRI), the Biodosimetry program addresses clinical symptoms of radiation exposure, reach back reference capabilities. Biodosimetry is the only method to detect, assess and estimate radiation dose exposure and is critical for military missions and saving lives. AFRRI prepared an in-depth Business Case Analysis and is strategically poised to establish the DoD’s Advanced Biodosimetry Network (DABN), meeting the objective of US Senate Report SR 114-63. The established network would be complemented with the Diagnostic Biodosimetry Laboratory that aligns with the DoD Clinical Laboratory Improvement Program (CLIP). CLIP describes requirements within the respective DoD’s Active and Reserve Components and facilities under their supervision to include oversight, inspections, proficiency testing (PT), personnel standards, and training in laboratories performing testing on human specimens so that clinical decisions can be made [reference DoDI 6440.02]”. The Biodosimetry laboratory also received clinical specimens from the Fukushima radiation accident in 2011, showcasing USUHS/AFRRI’s capabilities to support the DoD in case of an accidental radiation exposure or radiological terrorism scenario. The Biodosimetry program capitalizes on findings under PE 0602787HP, Medical Technology, and from industry and academia to advance novel medical countermeasures into and through pre-clinical studies toward newly licensed products. Research findings are focused to advance the development and production of the following: (1) To establish clinically certified processes to permit rapid assessment of radiation exposed specimens; (2) To assess radiation exposure by developing and providing biological and biophysical dosimetry capabilities for acute, protracted, and prior radiation exposure; (3) To develop novel triage protocols for rapid assessment of radiation exposure; (4) To establish equipment triage automation to support the ability to manage mass-casualty radiation incidents around the globe.
Document Details
- Document Type
- Project
- Publication Date
- Oct 01, 2024
- Source ID
- 242A_0603002DHA_2_0130_PB_2024
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