Preventing Violent Explosive Neurologic Trauma (PREVENT)
Abstract
The Preventing Violent Explosive Neurologic Trauma (PREVENT) program illuminated the causes of blast-induced traumatic brain injury (TBI), an injury that while previously described in the warfighter population, has been referred to as a potential "hidden epidemic" in the current conflict. PREVENT used a variety of modeling techniques based on in-theater conditions to assess potential TBI caused by blast in the absence of penetrating injury or concussion. Research worked to create a model that can be directly correlated to the epidemiology and etiology of injury seen in returning warfighters, and attempted to determine the physical and physiological underpinnings and causes of the injury. Raw data was collected from in-theater blast gauges, along with medical and event reports to form a comprehensive analysis. As part of the mitigation and treatment strategy, candidate therapeutics were tested in order to alleviate inflammation from both acute and chronic injury.
Document Details
- Document Type
- Accomplishment
- Publication Date
- Oct 01, 2014
- Source ID
- 24c43186cc188c1784dcf9aac7af437b
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- Root: BIOMEDICAL TECHNOLOGY