Systems Biology
Abstract
This project encompasses two efforts to support applied research and impact medical research relevant to the Soldier. (A) The core capability for multidisciplinary applied research in systems biology enables integration and analysis of complex data from human and animal studies and development of in silico (via computer simulation) network models, allowing us to differentiate between molecular signatures of psychological illness, diseases, and other medical conditions for the Soldier, such as heat injury. This core capability has supported transition of research to clinical applications faster, cheaper and better than standard approaches because many forms of data from numerous studies are integrated into a consolidated personalized clinical environment used to treat Soldiers more effectively. (B) Applied research is to identify toxicity-altered pathways (scientists can infer human harm from chemicals on the basis of how they change the activity of biochemical steps in cells and animals) enabling us to identify toxic environmental chemicals and materials as well as understand the injury mechanisms of toxic environmental chemicals and to develop molecular and physiological markers of toxicity for a next generation diagnostic system to support early exposure medical decisions.
Document Details
- Document Type
- Accomplishment
- Publication Date
- Oct 01, 2015
- Source ID
- 3580cfe376eb90d74e75779dedc29fd0
Related Documents
- Root: MEDICAL TECHNOLOGY