CoE-Gynecological Cancer Center of Excellence (USUHS)
Abstract
The Gynecologic Cancer Center of Excellence (GYN-COE) is an integrated translational research program aimed at development of companion biomarkers and assays, clinical decision support tools, risk assessment algorithms, quality improvement initiatives, treatments, and interventions for patients with gynecologic tumors and cancers, among a growing proportion of active duty women in the Armed Services, veteran and retired populations. Molecular profiling of pre-cancerous and malignant lesions has also enabled development of diagnostic and chemo-preventive interventions across the most common pathologic uterine conditions, rare variants, and the aggressive and deadly metastatic and recurrent malignancies that affect women and corresponding readiness. The GYN-COE has been the leading research program in the U.S. to identify clinical features, biologic etiologies, and social determinants underlying racial and ethnic disparities in gynecologic cancers using population based as well as translational research methods. The GYN-COE program features both the largest tissue laser capture microscopy facility as well as the most robust mass spectrometry-based proteomics facility in the DOD, enabling the program to assess the generalized relevance of GYN-COE discoveries in other cancers that impact service members and readiness. The comprehensive research program supports the training of subspecialty gynecologic oncology surgeons, a fellowship program that has trained advanced pelvic surgeons to support wartime efforts for the past 50 years. The program also educates and trains medical students, interns and residents in women’s health, telemedicine, wellness, wound-healing, hemorrhage, infections, pain management, resistance, resilience, palliative care and evidence-based medicine. The program has partnered with the National Cancer Institute in its educational and investigative activities over the past 20 years becoming a pillar program for the Murtha Comprehensive Cancer Center and the Uniformed Services University. The GYN-COE has also strengthened cancer capabilities, advanced the federal precision oncology initiatives, contributed to the COVID-response, enabled delivery of equitable care to female service members, veterans and beneficiaries, and ensured readiness of the female fighting force by addressing their gender-specific medical conditions.
Document Details
- Document Type
- Project
- Publication Date
- Oct 01, 2023
- Source ID
- 379B_0603115DHA_2_0130_PB_2023
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