Advanced Diagnostics & Therapeutics Research & Development (AF)
Abstract
This project provides applied research funding needed to perform research in the area of diagnostic assay development/refinement for diseases of operational significance. This project area seeks to manage and support research activities designed to facilitate the clinical integration of genomic-based medicine across the AFMS. Research in genomic medicine seeks to initiate the transition of genomic research discoveries into clinical practice, specifically applying knowledge derived from the study of pharmacogenomics, cancer genomics, gene-environment interactions, and inherited disease genomics in Airmen and beneficiaries. The program funds seeks to promote ‘omic’-informed personalized medicine with an emphasis on targeted prevention, diagnosis, and treatment. The delivery of pro-active, evidence-based, personalized medicine will improve health in Warfighters and beneficiaries by providing care that is specific to the situation and patient, to include preventing disease or injury, early and accurate diagnosis, and selection of appropriate and effective treatment. Personalized medicine will reduce morbidity, mortality, mission impact of illness/injury, and healthcare costs while increasing health and wellness of the AF population and efficiency of the healthcare system. This applied research supports multiple focus areas, each of which represents an identified barrier/gap which must be addressed for successful implementation of ‘omic-informed personalized medicine. Focus areas for applied research include knowledge generation research; ethical legal and social issues/policy research; bioinformatics research; educational research; research for development of advanced genomic diagnostic system. Analyze genomics survey data to identify gaps in genomic education, and development of educational programs to correct these gaps. Plans are to utilize patient modeling algorithms to identify pharmacogenomics interventions that can improve patient health and reduce healthcare costs across the AFMS. Program aims to further conduct analysis in educational interventions for the proper use of genetic testing within the AFMS. Research for pharmacogenomics for anti-depressants and pain medication within the AFMS is also planned. Analysis of methodologies and challenges associated with the establishment of an AFMS genome data repository for future implementation of genomic medicine is a key program component.
Document Details
- Document Type
- Accomplishment
- Publication Date
- Oct 01, 2020
- Source ID
- 3bc5191922ce695c08b3d792d01351ab