Gene Editor Enabled Diagnostics & Biosurveillance
Abstract
The Gene Editor Enabled Diagnostics & Biosurveillance program aims to develop fieldable, low-cost, programmable and reconfigurable diagnostic capabilities for rapid, specific, sensitive, and multiplexed detection and characterization of biological threats in military and public health scenarios. This program will investigate the design rules for high confidence diagnostic biosurveillance as well as develop agnostic pathogen detection and characterization platform technology for overall threat assessment. These design rules will inform advanced computational and machine learning approaches to scan genome data, algorithmically design probes and guides for optimal assay results, and characterize previously unknown organisms or threats. Additional work will develop assay architectures, reagents, and detection platforms to enable field-forward diagnostics and threat assessment characterization either at the point-of-care or in other areas of interest. Technology will have the same sensitivity, and reliability as tests conducted in hospital/central laboratories.
Document Details
- Document Type
- Accomplishment
- Publication Date
- Oct 01, 2024
- Source ID
- 57a7a1b6ed6482fb885ff982f477a6a1